Nicotine Mouth Spray Trials

Nicotine replacement therapy (NRT)  in the form of gums, patches, lozenges and nasal sprays have been around for awhile and are an option to help smokers who want to quit.  These NRTs deliver a steady dose of nicotine over the course of the day to help the smoker fight the cravings they have for nicotine.  But a new NRT in the form of a mouth spray is in the trial phase in Europe.  The mint spray used in place of a cigarette, up to four times an hour, provides a more quickly-absorbed dose of nicotine than other forms of NRT to fight cravings while the smoker tries to quit.

During the study involving 479 smokers, almost 14 percent who used the spray for three months had not gone back to smoking by the end of the trial period which lasted a year.  Only six percent of the smokers given a placebo spray were smoke-free at the one year mark.  The control group and the placebo group reported their cravings for cigarettes did diminished over time.  And both groups reported weight gain and mild-to-moderate side effects which included salivating too much, nausea, hiccups, and throat irritation.   Each group was tested at the end of the one year trial to determine if they went back to smoking.

Those in the study received “minimal” counseling and researchers felt that with more intensive counseling, along with NRT, the number of those who quit could be higher, up to 25 percent.

The Nicorette QuickMist mouth spray is made by McNeil AB.

Read the entire story here.

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